How To Produce Antihistamine Medicine
⚠️ Before we dive into the production process please make sure you have a pharmacist certificate and you ensure you are qualified for doing the production to avoid taking human life, this might end you up in life sentence.
ANTIHISTAMINE MEDICINE PRODUCTION PROCESS STEP BY STEP INSTRUCTIONS
1) Ensure that the environment for the production is neat and the machines for this production are watched and linxed. Also before claiming that the machines are clean ensure that theirs a lab personnel assisting the production to avoid bacteria and deadly substances contaminating the antihistamine medicine.
2)get the required raw material for the production ready before starting the production and also ensure that where you are keeping the raw material is clean and also have AC that will increase the cooling temperature and also make sure that the raw materials are not expired.
3)before starting the production make sure that all the people involved in the production, including the pharmacist are putting on the necessary kits for the production like
– Lab coat
– lab shoes
– nose mask
– gloves
And other necessary kits, this kits are not only for the purpose of ensuring that the medicine is not contaminated but also to ensure that the people involved in the production are not harmed by raw chemicals (raw material), and those doing the production should avoid taking raw materials whether it’s eatable or not.
4) Ensure that electricity is constant and ready during the production in order to avoid medicine developing unnecessary issues during production.
REQUIRED RAW MATERIALS FOR ANTIHISTAMINE MEDICINE PRODUCTION
1)paracetamol raw material
2)Corn starch
3)lactose
4)paraben
5)phenylephrine
6)chlorphenamine
7)gelatin
Before the production process start, a quick reminder ensure everyone involved in the production are putting on production kits to avoid danger and ⚠️ remove hand from moving machine, and also ensure that everyone doing the production watched their hands with ethanol before putting on their gloves.
MACHINES FOR THE PRODUCTION STARTS WITH
1)large electric kettle
2)weighing machine
3)rapid mixer granulator
4)breakflu dryer
5)rapid grinding machine
6)blending machine
7)compressing machines
The Antihistamine medicine will go through all this machine in order to ensure successful production.
MIXING PROCESS
Bring out all the above mention raw material.
before starting mix use the large electric kettle to boil water and ensure that the water is a treated water which came from the dispense area of the production area
-weigh 15kg of Starch (raw material) and pour it inside the rapid mixer granulator.
-weigh and pour 20kg of lactose inside the rapid mixer granulator.
-weigh and pour 65kg of paracetamol inside the rapid mixer granulator.
-weigh and pour 200g of paraben inside the rapid mixer granulator.
-weigh and pour 0.8kg of phenylephrine inside the rapid mixer granulator.
-weigh and pour 0.5kg of chlorphenamine inside the rapid mixer granulator.
Then dry mix it for 10mins by turning on the rapid mixer granulator on, while your rapid mixer granulator is set for 10mins you should prepare paste for the wet mixing by weighing this raw materials one by one then use then to prepare the paste.
-Firstly measure and pour 5kg of starch and keep it on a separate bowl
-measure and pour 500g of Gelatin, then keep it on a different bowl
-after ensuring that the hot water on the kettle have boiled then you get ready. The preparation of starch paste is actually prepared the way pap is being prepared, if you are confused then you can simply watch video of how to prepare pap.
– so pour 4 litres of ordinary treated water from dispense inside a big bowl, then pour in the 5kg of starch inside it then turn it till all the starch dissolves turning milky in colour.
-then pour in the hot water slowly and steady, as you are pouring in the hot water and turning, also pour in the 500g of gelatin slowly and steady till it finishes
– as you are pouring in the hot water you will notice that the starch is getting ticker, once it gets small ticker stop pouring in the hot water simply continue turning it.
– after preparing the paste ensure that the gelatin inside the starch paste all dissolved and also mind the amount of water you add during the starch paste to avoid the antihistamine medicine from becoming so liquid which might spoil the antihistamine medicine because it will be difficult to dry.
After dry mixing for 10 mins (granulating)
-pour the starch paste inside the rapid mixer granulator, please ensure that the gelatin on the starch paste have all dissolved.
-Then start wet mixing by putting off and putting on the rapid mixer granulator or you put it on slow mode, while turning you should constantly check it till the rapid mixer granulator read 2 (wet limit).
After wet mixing (granulating) it for any required amount of time it might take, get the breakflu dryer ready then bring out the breakflu dryer mesh, move it to the rapid mixer granulator discharge area and ensure that the rapid mixer granulator discharge area is inside the mesh to avoid discharging medicine on the ground, and before moving the mesh to discharge area make sure that the under of the mesh is fixed well by a mechanical engineer or a professional handling the breakflu machine. After moving the mesh to the discharge area, discharge the antihistamine medicine wet granules slowly by turning on and off of the rapid mixer granulator or by reducing the speed of the rapid mixer granulator, after successfully discharging the the antihistamine medicine inside the breakflu dryer mesh then move it to the breakflu dryer.
DRYING PROCEESS OF ANTIHISTAMINE MEDICINE
Drying antihistamine medicine takes few hours, it might take long because it’s paste is only water.
– push the breakflu dryer mesh inside the breakflu dryer where it belongs.
– dry for 45mins interval for 5 times , and for each interval turn the antihistamine medicine inside the mesh then put it back in the breakflu dryer for another interval, repeat process till 5 times of each being 45 minutes this it is to reduce hardness of the antihistamine medicine during grinding process.
– after drying move the mesh to rapid grinding machine.
GRINDING PROCESS
this requires no much process, all you have to do is set up the grinding machine, and make sure there’s a container where the grinded antihistamine medicine granules will be entering and also ensure that the container or the machine is not wet on anyway
– grind the antihistamine medicine and after grinding cover it and move it to the blending machine.
BLENDING PROCESS
start by measuring and pouring the required amount of the grinded antihistamine medicine granules inside the blending machine then add the required raw material according to the formula provided by the pharmacist.
After blending store it back on another clean dry container and move it to the compressing machine.
COMPRESSING PROCESS
this process require a professional or an engineer to set up the required mole size/shape of the antihistamine medicine. after compressing, Few of The antihistamine medicine will be taken to the lab by lab personnel to ensure that the antihistamine medicine is safe.
CONCLUSION
This process is how to produce antihistamine medicine, if you are interested in knowing how to produce other medicines visit my other post, ⚠️ please all the warnings on this article is not a joke, and will result to a serious issue, please ensure you have the right to do anything involving production before going to production to avoid substaining serious injury from machines or causing damage to the life of millions of people out there, which might even get you death sentence, STAY SAFUU.
